My research lies at the intersection of genomics, neuroscience, and bioinformatics. Our lab delves into the complexities of epigenomic regulation in the brain, influenced by both inherent genetic factors and life experiences. Developing and utilizing innovative single-cell multi-omics and spatial genomics methodologies, along with neural circuit analysis and integrative computational approaches, we interrogate dynamic epigenomic and gene regulation at the levels of individual cell types, brain regions, and neural circuits. Additionally, we aim to elucidate how life experiences interplay with individuals' genetics to leave enduring imprints on epigenetic regulation, thereby affecting behavior and the propensity for brain disorders.
Zhuzhu Zhang, PhD
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Assistant Professor of Human Genetics
Assistant Professor of Neuroscience Institute
Committee on Computational Neuroscience
Committee on Genetics, Genomics and Systems Biology
Committee on Neurobiology - Research and Scholarly Interests: Brain development and disorders, Epigenomics, Gene Regulatory Networks, Genetics, Neuroscience, Psychiatric disorders, Single-cell genomics
- Websites: Research Network Profile
- Contact: zhuzhuzhang@uchicago.edu
- Graduate Programs: Computational Neuroscience, Genetics, Genomics & Systems Biology, Neurobiology, Committee on Development, Regeneration, and Stem Cell Biology, Human Genetics, PhD Program in Neurobiology